A Bible Study For Women Suffering From Perimenopausal and Menopausal Changes

I’ve met a few women who have told me they never had PMS or mood swings related to hormone cycles, and I always say ‘You are blessed!’. But for most of us, that’s not the case. Blame it on Eve, or chemicals in the water, or sin, or genetics, being a woman can be a moody roller coaster at times, even when we know Jesus! But thankfully Jesus knows that we are dealing with the flesh and he is full of mercy and grace for those who put their trust in Him. Yet we can often feel defeated and guilty for not feeling joyful at all times and the devil can certainly accuse us when we are struggling.

I wrote the following short Bible Study to help women who need some extra encouragement to keep leaning on Jesus on the bad days. Remember, no matter what, He still loves you!

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Steady in the Storm: A Bible Study for Women Facing Hormonal Changes

Our bodies and emotions go through many transitions — PMS, perimenopause, menopause, and other hormonal changes. These can stir deep emotions and even spiritual battles. Yet the Lord who created us understands every part of our being.

Psalm 103:14: “For He knows how we are formed, He remembers that we are dust.”

When everything inside feels unstable, remember: God never changes. He is our steady anchor when emotions, relationships, and bodies shift like sand.

Hebrews 13:8: “Jesus Christ is the same yesterday and today and forever.”


Hormonal fluctuations can cause emotional highs and lows that seem beyond our control. God never shames us for our tears or frustrations. Instead, He invites us to bring every thought to Him — to exchange our anxiety for His peace.

Philippians 4:6–7: “Do not be anxious about anything… and the peace of God, which transcends all understanding, will guard your hearts and your minds in Christ Jesus.”
Psalm 42:11: “Why, my soul, are you downcast? … Put your hope in God, for I will yet praise Him.”

Encouragement:
When you wake up discouraged or angry for no clear reason, know that God already understands. He sees the chemistry, the weariness, and the longing behind it all. Invite Him into your storm. His love is greater than your emotions, and His presence will calm the waves in your soul.

Questions:

  • When emotions take over, what can I do to turn toward God rather than retreat inward?
  • How might I make prayer my first response, not my last resort?

Hormonal changes often bring exhaustion, hot flashes, pain, and sleepless nights. God never measures our worth by our energy level or what we accomplish. He offers rest for our bodies and refreshment for our souls.

Matthew 11:28–29: “Come to me, all you who are weary and burdened, and I will give you rest.”
Isaiah 40:29–31: “He gives strength to the weary and increases the power of the weak… those who hope in the Lord will renew their strength.”

Encouragement:
God’s invitation to rest is not permission to give up — it’s a call to trust Him. When your strength runs out, His grace begins. Even if you can’t do everything you once could, you can rest in knowing He is still working in you. Sit in His presence, breathe deeply, and remember you are loved — not for what you do, but for who you are in Him.

Questions:

  • Where am I pushing myself too hard instead of resting in God’s care?
  • How can I let my “to-do list” become a “trust list”?

Changing bodies, fluctuating weight, or fading youth can make us critical of ourselves. Yet God’s love never wavers with our appearance or abilities.

Psalm 139:14: “I praise You because I am fearfully and wonderfully made.”
Romans 8:1: “There is now no condemnation for those who are in Christ Jesus.”
1 Samuel 16:7: “The Lord does not look at the things people look at… the Lord looks at the heart.”

Encouragement:
God made you intentionally — every feature, every stage, every season. When you feel less than beautiful, remember you are clothed in His righteousness and crowned with His glory. You don’t need to strive for perfection; simply rest in being His beloved daughter.

Questions:

  • What truth from Scripture can I speak aloud when self-criticism starts?
  • How can I treat my body with grace and gratitude today?

Emotional ups and downs can strain relationships. You may feel unseen, misunderstood, or distant from loved ones. God knows your heartache and offers His companionship when others fall short.

Ephesians 4:2–3: “Be completely humble and gentle; be patient, bearing with one another in love.”
Ecclesiastes 4:9–10: “Two are better than one… If either of them falls down, one can help the other up.”

Encouragement:
You are never truly alone. The Lord sees every silent tear and hears every prayer whispered in frustration. Ask Him to heal what’s broken — not only in your relationships, but in your own heart. When you lean on Him, He gives you patience, softness, and understanding that human effort can’t create.

Questions:

  • How can I invite God’s Spirit into my home and my relationships today?
  • Am I willing to let God teach me to love, even when I don’t feel loved in return?

This season may bring new questions: “Who am I now that the kids are grown?” “What’s next for me?” “Does God still have a purpose for my life?” The answer is yes — His purpose never expires.

Isaiah 46:4: “Even to your old age and gray hairs I am He… I will sustain you and I will rescue you.”
Ephesians 2:10: “For we are God’s handiwork, created in Christ Jesus to do good works.”

Encouragement:
God never wastes a season. What feels like loss can become renewal. He may be calling you to pour your wisdom into others, to slow down and listen more deeply, or to rediscover gifts you once set aside. Let Him redefine your identity — not as what you’ve done, but who you are in Him: cherished, chosen, and useful for His glory.

Questions:

  • What new doors might God be opening for me in this stage of life?
  • How can I live with expectancy instead of fear about the future?

For many women, this season isn’t only about hormones — it’s layered with grief: the loss of a spouse, parent, or friend… a child walking away from faith… financial hardship… or a serious diagnosis. These burdens can feel unbearable on top of emotional and physical strain. Yet even in the deepest sorrow, God remains near.

Psalm 34:18: “The Lord is close to the brokenhearted and saves those who are crushed in spirit.”
Matthew 5:4: “Blessed are those who mourn, for they will be comforted.”
Philippians 4:7: “And the peace of God, which surpasses all understanding, will guard your hearts and your minds in Christ Jesus.”

Encouragement:
When you can’t see the way forward, take one day at a time. You don’t have to figure out tomorrow — God is already there. He collects your tears (Psalm 56:8) and understands your pain more deeply than any human could. Even in grief, you can glorify Him by trusting His goodness through the tears. Some days that simply means whispering, “Lord, I still believe You are good.” That’s worship.

When you lean into His strength instead of your own, He gives you peace that doesn’t make sense to the world — a peace that steadies you when nothing else can.

Questions:

  • What loss or fear am I carrying that I need to lay at Jesus’ feet today?
  • How can I remind myself that grief is not a sign of weak faith, but an invitation to deeper trust?

Unresolved pain often bubbles up as anger. But anger is not the enemy — sin is. God invites us to bring our frustrations to Him instead of letting them harden our hearts.

Ephesians 4:26–27: “In your anger do not sin… do not give the devil a foothold.”
James 1:19: “Everyone should be quick to listen, slow to speak and slow to become angry.”

Encouragement:
God knows the story behind your anger — the exhaustion, the disappointments, the unspoken needs. You don’t have to hide your feelings; you just have to hand them over. Tell Him everything, then let His Spirit replace bitterness with compassion and sorrow with peace.

Questions:

  • What am I holding onto that God is asking me to release?
  • How can I practice surrender instead of control today?

Though our bodies change and our hearts ache, God is renewing us day by day. Every trial can become a testimony of His faithfulness.

2 Corinthians 4:16: “Though outwardly we are wasting away, yet inwardly we are being renewed day by day.”
Romans 15:13: “May the God of hope fill you with all joy and peace as you trust in Him.”

Encouragement:
This season is not the end — it’s transformation. The same power that raised Jesus from the dead is working in you, shaping you into a woman of deeper faith, wisdom, and beauty. When bad days come, lean not on your own understanding, but on God’s eternal strength. You are held, loved, and never forgotten.

Questions:

  • What promise of God can I cling to this week?
  • Who around me needs the same hope God is giving me?

When your heart is weary and your hormones are wild, God’s love does not waver. He is the anchor in your storm and the gentle hand guiding you through every wave.

Prayer:
“Lord, You know the struggles of my body and the aches of my heart. When I am overwhelmed, remind me that You are near. Help me take one day at a time, leaning on You for peace that passes understanding. Even through tears, I will give You glory, for You are my strength and my song. Amen.”


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4 comments

  1. That’s a great idea, Paula. Well done!

    I think this is a season in life when we really have to transition from taking care of others to taking care of ourselves. Best way to take care of ourselves is to draw closer to the Lord and really invest in our relationship with Him. Menopause is a huge gift and of course it often doesn’t feel like that at the time, but it’s a bit like childbirth, a process that bears some genuine fruit at the end. Like a lot of things in life, gratitude, thanking the Lord for blessing us with the season, can really help shift our perspective.

    • Totally agree . I’m past the worst of it and into the aging husband phase . But for those in the early stages, it’s rough . I hope this study will encourage them to lean in .

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